Estrovera by Metagenics


The New Gold Standard for Menopausal Relief* Estrovera is a natural option that features ERr 731, a special extract of Siberian rhubarb, demonstrated in clinical studies to significantly reduce menopausal symptoms—offering an effective and safer option for both peri- and postmenopausal women. Clinically shown to dramatically reduce the number of daily hot flashes and relieve a wide range of other symptoms, to a similar extent as estrogen-based therapies and exceed reported results of other phytoestrogen and botanical approaches. Multiple short- and long-term studies with over 400 women confirm efficacy and predicted safety, for over 20 years.

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Estrovera provides effective relief for multiple menopause symptoms, including hot flashes*

  • In a 12-week clinical study with ERr 731, perimenopausal women reported significant improvements in symptoms—including hot flashes and anxiety—within just 28 days (compared to placebo)*3,4
  • In another 12-week clinical study, ERr 731 reduced median number of daily hot flashes from 12 to 2*5
  • In a 6-month study, ERr 731 demonstrated progressive relief of multiple symptoms measured by the Menopause Rating Scale (MRS), including:*1
    • Negative mood, irritability & anxiety
    • Joint and muscle discomfort
    • Physical/mental exhaustion
    • Sleep disturbances
    • Hot flashes/night sweats
  • In a 2-year study with ERr 731, ~83% reduction of the total MRS II score was maintained from 60 weeks to 108 weeks*†2
  • Estrovera provides a clinically effective dose of ERr 731 in just 1 tablet daily*